PRISMA 2020 - GRADE - RoB 2 - No R Required

From literature search to forest plot - All in one place.

The complete systematic review platform. Search 9 databases, screen studies, extract data, assess risk of bias, run GRADE-compliant meta-analysis, and generate publication-ready figures -- all in your browser.

Free Trial · 1 project · All features included

Live meta-analysis output
61
Studies included
9
Databases searched
1828
Records identified
Pooled SMD: −1.21 (95% CI −1.43 to −0.99)
−2.0Null (0)+2.0
I² = 62.1% p < 0.001 τ² = 0.042 (DL) k = 61 studies Egger's p = 0.297 PRISMA 2020 ✓ GRADE ✓ RoB 2 ✓
9 databases simultaneously
No R or Python required
PRISMA 2020 compliant
Verified statistical formulas
Lifetime access · one-time payment
Free trial · no credit card
The impact
90%+
Reduction in time per review

A traditional systematic review takes months across disconnected tools. Verflux integrates every step. Researchers complete their reviews in days, not months.

No more spreadsheet chaos All screening, extraction, and analysis in one structured database
Search 9 databases in one click No multi-tab searching or manual deduplication
Instant forest plots & PRISMA Publication-ready figures generated in seconds, not hours
Real-time collaboration Blind dual-reviewer screening with automated conflict detection
Structured methods text Auto-generated methods section ready to paste into your manuscript
What's included

Everything a systematic reviewer needs

Every feature in every plan. No modules, no add-ons.

01
🔍

Multi-database search

PubMed, Scopus, Europe PMC, CrossRef, OpenAlex, Google Scholar, and Web of Science. Boolean operators, year ranges, study-type filters. Cross-database duplicate detection.

02
📋

Screening

Title/abstract and full-text stages. Bulk decisions, keyboard shortcuts, abstract viewer. Blind dual-reviewer mode with conflict resolution.

03
🗂️

Data extraction

Arm-level extraction for continuous and dichotomous outcomes. Auto-fill from DOI or PMID. Unlimited outcomes per study.

04
⚠️

Risk of bias

RoB 2, ROBINS-I, Newcastle-Ottawa Scale, QUADAS-2, AXIS. Domain-level traffic-light ratings with overall judgement.

05
🏅

GRADE assessment

Certainty ratings per outcome. Five downgrade and three upgrade domains. Evidence summary table auto-generated.

06
📐

Statistical engine

DL and PM random effects, fixed-effect IV. Hedges g, subgroup analysis, leave-one-out sensitivity, Egger test.

07
📈

Figures

Forest plot with weight-proportional squares and prediction intervals. Funnel plot with confidence region. High-DPI PNG download.

08
📄

PRISMA 2020

Correct three-phase flow diagram. Every value editable with live preview. Saves per project. PNG download.

Why Verflux

Built for researchers,
not for statisticians

Every other tool requires R, Python, or expensive software licenses. Verflux runs in your browser and handles the entire pipeline end-to-end.

Verflux RevMan R (meta pkg) Rayyan Stata
No software install required
No R / Python needed
9-database search built-in
Screening + extraction + RoB Partial
GRADE certainty assessment
Forest & funnel plots
PRISMA 2020 flow diagram
Real-time collaboration
Begg's + Egger's + Orwin's N
One-time payment (no sub.) Free $500+/yr Free $500+
Works on any device/OS Win/Mac Any Any Win/Mac
Guided pipeline

Eight steps, one platform

Each stage feeds into the next. Navigate forward or backward at any point.

01

Search

Seven databases simultaneously. Boolean operators and study filters. Duplicates removed automatically.

02

Screen

Bulk include/exclude/maybe decisions. Full-text stage with exclusion tracking. Blind dual-reviewer mode.

03

Extract

Arm-level extraction for continuous and dichotomous outcomes. Auto-fill from DOI or PMID.

04

Risk of bias

Six validated instruments. Traffic-light summary table generated automatically.

05

GRADE

Certainty of evidence per outcome across downgrade and upgrade domains. Evidence summary table.

06

Analysis

Random-effects and fixed-effect meta-analysis. Subgroup analysis, sensitivity analysis, Egger test.

07

Plots

Forest and funnel plots with prediction intervals. High-resolution PNG download.

08

Report

PRISMA 2020 diagram, methods text, and exports in CSV, JSON, RIS, and HTML.

By the numbers

Designed for scientific rigour

9
Databases searched simultaneously
19
Statistical formulas verified
6
Risk of bias tools supported
90%+
Time saved vs traditional toolchains
5
Effect measures (MD, SMD, RR, OR, RD)
300 DPI
Export resolution for all figures
PRISMA 2020
Fully compliant flow diagram
PRISMA 2020
Fully compliant
From researchers

What scientists say

★★★★★

"I completed a 61-study meta-analysis in under a week. What used to take months of juggling PubMed, Excel, and R now happens in one browser tab. The forest plots are publication-ready."

SA
Dr. S. Ahmed
Assistant Professor, Internal Medicine
★★★★★

"The GRADE assessment and PRISMA 2020 flow diagram generation saved me enormous time. The statistical output matches R metafor, but I do not need to write a single line of code."

MK
Dr. M. Khan
Systematic Review Researcher
★★★★★

"Finally a tool that handles dual-reviewer screening AND meta-analysis in one place. The conflict resolution queue is brilliant. Highly recommend for any research team."

FA
Prof. F. Ali
Department of Evidence-Based Medicine
Simple pricing

One-time payment. Lifetime access.

Pay once, use forever. No subscriptions, no renewals.

Trial
$0
one-time · lifetime access
  • Demo data import to test all features
  • 1 active project
  • 0 collaborators
  • All analytical tools
  • Literature search (9 databases)
  • Screening & extraction
  • Risk of bias (6 tools)
  • GRADE assessment
  • Meta-analysis engine
  • Forest & funnel plots
  • PRISMA 2020 diagram
Starter
$30
one-time · lifetime access
  • 1 active project
  • 5 collaborators per project
  • All analytical tools
  • Literature search (9 databases)
  • Screening & extraction
  • Risk of bias (6 tools)
  • GRADE assessment
  • Meta-analysis engine
  • Forest & funnel plots
  • PRISMA 2020 diagram
  • CSV, JSON, RIS, HTML exports
  • Lifetime access
Unlimited
$200
one-time · lifetime access
  • Unlimited active projects
  • 20 collaborators per project
  • All analytical tools
  • Literature search (9 databases)
  • Screening & extraction
  • Risk of bias (6 tools)
  • GRADE assessment
  • Meta-analysis engine
  • Forest & funnel plots
  • PRISMA 2020 diagram
  • CSV, JSON, RIS, HTML exports
  • Lifetime access

One-time lifetime payments  ·  Stripe, PayPal, Easypaisa & JazzCash accepted
Pakistani researchers: Starter ~PKR 8,400 · Professional ~PKR 14,000 · Unlimited ~PKR 28,000

Need more projects? Extra Project slots ($30 each, lifetime) are available from your dashboard after signing up.

Frequently asked

Got questions?

Is Verflux free to use? +
Yes. The Trial plan gives full access to all analytical features with no credit card required. Paid plans unlock exports and more project slots.
Do I need R or Python? +
No. Everything runs in your browser. Meta-analysis, forest plots, and all statistics are computed server-side. No software installation required.
Which databases are searched? +
PubMed/MEDLINE, Scopus, Europe PMC, CrossRef, OpenAlex, Google Scholar, and Web of Science — seven databases simultaneously with automatic deduplication.
Are payments one-time or monthly? +
One-time, lifetime payments. Pay once and your plan never expires. No subscriptions, no renewals. Add extra project slots anytime from your dashboard.
What risk of bias tools are included? +
Cochrane RoB 2 (RCTs), ROBINS-I (non-randomised), Newcastle-Ottawa Scale, QUADAS-2 (diagnostic), and AXIS (cross-sectional).
Can I collaborate with other reviewers? +
Yes. Invite co-reviewers to your project. Blind dual-reviewer screening with automated conflict detection. Cohen's kappa calculated.
What payment methods are accepted? +
Stripe (Visa, Mastercard, Amex), PayPal, Easypaisa, and JazzCash. PKR prices shown at checkout.
How accurate are the statistical results? +
Every formula is verified against primary published references: Borenstein (2009), Hedges (1981), DerSimonian and Laird (1986), Egger et al. (1997).
Can I export my data and figures? +
Yes — on all paid plans. Formats: CSV, JSON, RIS, Word (.docx), HTML. Forest and funnel plots export as 300 DPI PNG.
Is Verflux PRISMA 2020 compliant? +
Yes. The PRISMA 2020 flow diagram is built from your project data. Downloads as 300 DPI PNG. A 27-item checklist is included.
What happens if I don't upgrade? +
Your account and all data remain permanently accessible. After the 3-day trial, export features are locked until you upgrade.
Can I use Verflux for multiple reviews? +
Yes — paid plans support multiple active projects. Professional includes 3 projects, Unlimited includes unlimited projects.
Academic use

Cite Verflux in your publication

If Verflux supported your systematic review or meta-analysis, please cite it so other researchers can find and use the tool.

APA 7th Edition — recommended
Rehman, N. U. (2026). Verflux: A browser-based platform for systematic reviews and meta-analysis (Version 1.0) [Software]. https://verflux.com
Vancouver / ICMJE
Rehman NU. Verflux: a browser-based platform for systematic reviews and meta-analysis [Software]. Version 1.0. 2026. Available from: https://verflux.com
Harvard
Rehman, N.U. (2026) Verflux: a browser-based platform for systematic reviews and meta-analysis, Version 1.0 [Software]. Available at: https://verflux.com (Accessed: 15 May 2026).
BibTeX / LaTeX
@software{verflux2026, author = {Rehman, Naeem Ur}, title = {{Verflux}: A browser-based platform for systematic reviews and meta-analysis}, year = {2026}, version = {1.0}, url = {https://verflux.com}, note = {[Software]} }
Suggested methods section wording — copy & paste into your manuscript
Literature screening, data extraction, risk of bias assessment (RoB 2, ROBINS-I, NOS, QUADAS-2), GRADE certainty of evidence ratings, random-effects meta-analysis (DerSimonian–Laird and Paule–Mandel estimators), and forest and funnel plot generation were performed using Verflux (Rehman, 2026), a browser-based systematic review and meta-analysis platform.

Ready to start your review?

Create a free account and work through your first systematic review entirely online. Upgrade when you need to export.

3-day free trial · All analytical features · Upgrade anytime · Lifetime access